Figure 6.
DNA rearrangement at common retroviral integration sites. Southern blot analysis was carried out using 5 μg genomic DNAs extracted from Tg/BXH2 leukemias. The leukemia samples with rearrangements are indicated as + above the sample ID. Restriction enzymes used in each blots are indicated. The size of DNA was indicated in kilobase. (A) Meis1 using the Meis1 3′ probe. Tumors with Meis1 integration at the 3′ region show DNA rearrangement. (B) Dnalc4. (C) Fcgr2b/Fcrl. (D) Con1. (E) Con2.

DNA rearrangement at common retroviral integration sites. Southern blot analysis was carried out using 5 μg genomic DNAs extracted from Tg/BXH2 leukemias. The leukemia samples with rearrangements are indicated as + above the sample ID. Restriction enzymes used in each blots are indicated. The size of DNA was indicated in kilobase. (A) Meis1 using the Meis1 3′ probe. Tumors with Meis1 integration at the 3′ region show DNA rearrangement. (B) Dnalc4. (C) Fcgr2b/Fcrl. (D) Con1. (E) Con2.

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