Transplant scheme. The xmd dogs were given 920 cGy or 200 cGy TBI on day 0, followed by HCT with G-CSF–mobilized PBMCs and bone marrow from DLA-identical littermates. Following one muscle biopsy, 4 recipients were given G-CSF for 5 days. Myofiber transplant study was used in 3 recipient dogs 9 months after HCT. Muscle biopsies were performed before and after HCT at different time points. CSP was used for postgrafting immunosuppression. TBI indicates total body irradiation; HC transplant source, G-CSF–mobilized PBMCs and bone marrow cells from DLA-identical littermate; MB, muscle biopsy; CSP, cyclosporine, 15 mg/kg orally twice a day, days -2 through +35; G-CSF, granulocyte colony-stimulating factor, 5 mg/kg subcutaneously twice a day for 5 days; and MFE, muscle fiber transplant.