hOCT1 and MDR1 expression in cell lines and primary CML cells. RT-PCR products were run on an agarose gel to show expression of the hOCT1 and MDR1 genes. The expected 229-bp product for hOCT1 and the 455-bp product for MDR1 were present in VBL, CEM cell lines, and CML cell lines LAMA84, KYO1, and KCL22. Both hOCT1 and MDR1 were expressed in 4 cases of CP (CP1 to CP4) and 2 cases of AP (AP1 and AP2). The 472-bp product for GAPDH gene expression was present in all cell lines and CML cells.