Figure 1.
Dose-response plots of coagulation indices versus log vitamin K1 dose for study phase I. (A) Plot of mean change in INR from baseline after 7 days of supplementation with each dose of vitamin K1 (•). For each subject, the data set represents the means of 4 INR values taken during the week. Plot of mean change in INR from baseline after first 24 hours (□). (B) Plot of the mean change in FIIc from baseline after 7 days of supplementation with each dose of vitamin K1. (C) Reciprocal plot of the mean change in INR after 7 days of supplementation with each dose of vitamin K1.