Figure 6.
![Figure 6. Effect of DTT on KCC activation by cell swelling in SS RBCs. (A) Rb influx activated by pH in SS RBCs with (•) and without (♦) preincubation with DTT (10 mM). DTT was present at 1 mM during nystatin treatment and Rb influx measurement. Data represent 4 independent experiments. (B) Normalized fluxes using maximal volume-stimulated flux (MCHC < 270 g/L [27 g/dL]) of control or DTT-treated SS RBCs. (C) Regulatory volume decrease in SS reticulocytes induced by cell swelling (to MCHC of 260 g/L [26 g/dL]) with and without DTT (n = 4). Error bars indicate standard deviation.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/104/9/10.1182_blood-2004-01-0112/6/zh80210468680006.jpeg?Expires=1723202157&Signature=5MvtNhmv~ZuBkLMNWiXTJnQe8rf1jAhCq01TxDk5tiwycdowabINam5MMMU-po8zf34WwK0VFmQ5xzKGVO-AniY3VUDUc4ZNqYtfxRQyhkF2ZgVDezEdlFWLAmke4qWce5znRgLLfW7pkonMLwjovbSvIX1kc~igVBYre9Ld1iFuR8mdCsXVsQLZQM7WgC9BJkY3I0IaRCq9iKgqSKlJYSkmBuuMuBYmtlRrZ8CNJhZ53gwe3fAlCJ-BovcEKsiJvaMTfcD41qk0Z9BsBUGurI7E0ZlxTQ2wWJmMBWFu2PRCXaefZDf5iFRFZT7Nhxuaja-zuV3KJvAuI19Vxby28A__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of DTT on KCC activation by cell swelling in SS RBCs. (A) Rb influx activated by pH in SS RBCs with (•) and without (♦) preincubation with DTT (10 mM). DTT was present at 1 mM during nystatin treatment and Rb influx measurement. Data represent 4 independent experiments. (B) Normalized fluxes using maximal volume-stimulated flux (MCHC < 270 g/L [27 g/dL]) of control or DTT-treated SS RBCs. (C) Regulatory volume decrease in SS reticulocytes induced by cell swelling (to MCHC of 260 g/L [26 g/dL]) with and without DTT (n = 4). Error bars indicate standard deviation.
