Figure 1.
MLN518 trough plasma concentrations 12 hours after oral gavage. (A) Treated with a single dose of MLN518 at 60, 120, 180, and 300 mg/kg. (B) Steady state at 180 mg/kg. (C) Cyclophosphamide at 180 mg/kg. (D) During bone marrow transplantation at 180 mg/kg.