Pharmacokinetic results. (A) Mean plasma concentration versus time curves for imatinib at steady state in children and adults. Data for adults are from Peng et al.¹⁹  h indicates hour; ng/mL, nanogram per milliliter; and mg/m², milligram per square meter. (B) Comparison of the imatinib AUCs at steady state in children and adults. Note: A 400-mg dose in adults is approximately 235 mg/m² and a 600-mg dose is approximately 350 mg/m². Data for adults are from Peng et al.¹⁹  AUC_(0-24h) (ng.h/mL) indicates area-under-the concentration-time curve, from time 0 to 24 hours (nanogram times hour per milliliter); mg/m², milligram per square meter; and n, number of patients. Error bars indicate SD.