Figure 5.
![Figure 5. Effect of DPI on bacterial survival and bacteria-induced ROS generation. Effect in human neutrophils stimulated with either opsonized E coli (A) or S aureus (B). Superoxide (ROS) production was measured by chemiluminescence and expressed as percentage of the maximal value obtained in the absence of DPI. Bacterial survival numbers represent the ratio of surviving CFUs per initial CFUs. Mean ± SEM of 5 (survival of E coli), 3(E coli-induced ROS production), 10 (survival of S aureus), and 5 (S aureus-induced ROS production) independent experiments are presented. In the case of E coli and S aureus, 100% ROS production corresponds to 3.52 and 4.46 nmol \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(\mathrm{O}_{2}^{{\cdot}-}\) \end{document} per 10 minutes per 106 PMNs, respectively.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/104/9/10.1182_blood-2004-03-1005/6/zh80210468710005.jpeg?Expires=1725024568&Signature=u7pLmfX6YuJAOetAklwPgioQ0f9GA3xVNuZqFyjCwCvDyCdr6RnTAwXh0Qs0chKnTBbNBmxnTdVJ2-~Hapc0bejYGetiK0Br1qSiSi7CuxMyL9LsCVrMD-QfizRpHa7NB6hZ9qEWODBX-esfV~MMAIjana~LwZFzlSxi5Y~Fn8a~VUN2dp288fomY3-Zi6EJKGHL3MPBRB2HwRPC5sKVOb27VZ7uJiu4K36yA~Jy7QGH6Kq3F3Eci5JXJjnYaVTsrPLkYZjPdJA4IiXXvGyaljhTciw2spkcyM0V1-K0zUCdz5EnuUCUwUT60mtY6XG0aZGoGASvFdPi4vHkTmSceA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of DPI on bacterial survival and bacteria-induced ROS generation. Effect in human neutrophils stimulated with either opsonized E coli (A) or S aureus (B). Superoxide (ROS) production was measured by chemiluminescence and expressed as percentage of the maximal value obtained in the absence of DPI. Bacterial survival numbers represent the ratio of surviving CFUs per initial CFUs. Mean ± SEM of 5 (survival of E coli), 3(E coli-induced ROS production), 10 (survival of S aureus), and 5 (S aureus-induced ROS production) independent experiments are presented. In the case of E coli and S aureus, 100% ROS production corresponds to 3.52 and 4.46 nmol \(\mathrm{O}_{2}^{{\cdot}-}\) per 10 minutes per 106 PMNs, respectively.
