Figure 3.
Survival of nude mice treated with A549 cells and hirudin. (A,B) Mice were treated with hirudin (20 mg/kg) 5 minutes before and 4 hours after intravenous injection of 1 × 106 A549 cells, and then every other day for 10 days. (C,D) Similar experiment with 5 × 106 cells.
