Gene expression array: RUNX3/ATRX ratio versus outcome. In children with de novo AML who harbor FLT3-MUs, the ratio of RUNX3 to ATRX may determine outcome. This same ratio in children with de novo AML and FTL3-WT (n = 45) did not correlate with outcome. In the top figure, EFS (%) is noted for samples with a ratio more than 0.8 (0%), from 0.4 to 0.8 (37%), and less than 0.4 (70%). Induc indicates induction.