Profiles of numerical abnormalities characterizing hypodiploidy with 30 to 39 chromosomes and near-triploidy. (A) Each vertical bar graph corresponds to a chromosome (sex chromosomes are analyzed together). For each chromosome, bars indicate the frequencies of monosomies (1 copy) and of disomies (2 copies); the abscissa represents the haploid set (1 copy) and the horizontal line represents the diploid set (2 copies). For each chromosome, frequencies are calculated from the cumulated numbers of copies from the 11 patients with hypodiploidy with 30 to 39 chromosomes. The maximum is observed for chromosome 1, which appears in 2 copies in all patients and the minimum value is observed for chromosomes 3, 15, and 17, which are monosomic in most patients. Therefore, the high values of the bar graph show the chromosomes often retained in pairs, and the low values point to the chromosomes that are frequently haploid. (B) Each vertical bar graph corresponds to a chromosome (sex chromosomes are analyzed together). For each chromosome, bars indicate the frequencies of disomies (2 copies), trisomies (3 copies), and tetrasomies (4 copies). The abscissa represents the haploid (1 copy) and the 3 horizontal lines represent the diploid (2 copies), triploid (3 copies), and tetraploid (4 copies) sets. For each chromosome, frequencies are calculated from the cumulated numbers of copies from the 13 patients with near-triploidy. Therefore, the highest values indicate the frequently trisomic or tetrasomic chromosomes, and the lowest values correspond to the frequently disomic chromosomes.