Immune function. After transplantation, there is a variable change in (A) CD3, (B) CD4, and (C) CD8 T-cell numbers as clonal T-cell populations decrease in number. After transplantation there are increasing numbers of (D) naive CD4 T cells and (E) naive CD8 T cells and increasing (F) T-cell proliferative responses to PHA. Changes in the (G) absolute eosinophil counts and (H) TREC values are shown. For panels A to C, the 25th percentile for children ages one to 6 years²²  is indicated by the dotted line. For panels D to E, the lowest value for 11 children aged one year²³  is indicated by the dotted line; the lowest value for 9 adults²³  is indicated by the solid line. In panel F, the mean for healthy adults is indicated by the solid line and the range of 2 standard deviations by the dotted lines. The patients' PBMC background proliferations (cells plus medium without mitogen) for the PHA assays (n=80) had a mean of 198 cpm with one standard deviation ranging from 74 cpm to 527 cpm. The normal control background had a mean of 173 cpm with one standard deviation ranging from 61 to 486 cpm.