Figure 2.
Figure 2. Liver biopsy. (A) The H&E-stained liver section is shown. (B-K) These panels represent immunohistochemical staining for CD20, CD3, CD2, CD4, CD8, CD5, CD68, TIA-1, granzyme B, and perforin. (L) Positive perforin staining is shown on a control section (spleen). All images are at × 500 magnification. The infiltrate is composed predominantly of CD8+ T cells with lack of perforin expression (FHL) and lack of CD5 expression, similar to flow cytometric findings.

Liver biopsy. (A) The H&E-stained liver section is shown. (B-K) These panels represent immunohistochemical staining for CD20, CD3, CD2, CD4, CD8, CD5, CD68, TIA-1, granzyme B, and perforin. (L) Positive perforin staining is shown on a control section (spleen). All images are at × 500 magnification. The infiltrate is composed predominantly of CD8+ T cells with lack of perforin expression (FHL) and lack of CD5 expression, similar to flow cytometric findings.

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