Effects of CIC maPLs on mouse pregnancy development. (A) Examples of macroscopic examinations of mouse embryos at day 10 after passive administration of maPLs or normal human IgG. (B) Rates of fetal resorptions after passive transfer of normal human IgG (n = 6), CIC3 (n = 7), CIC7 (n = 7), CIC11 (n = 6), CIC19 (n = 6), CIC15 (n = 10), and GL (n = 9). Horizontal brackets indicate mean values; horizontal bar with the star, statistical difference (P < .001).