Figure 6.
Figure 6. Flow cytometric analysis of hirudin or TFPI fusion protein on platelets from bone marrow–reconstituted mice after administration of LPS and l-NAME. Open profiles indicate antihirudin mAb for BMB6 → Hir and BMHir → B6 and antihuman TFPI mAb for BMB6 → TFPI and BMTFPI → B6; gray shaded profiles, isotype-matched control mAb.

Flow cytometric analysis of hirudin or TFPI fusion protein on platelets from bone marrow–reconstituted mice after administration of LPS and l-NAME. Open profiles indicate antihirudin mAb for BMB6 → Hir and BMHir → B6 and antihuman TFPI mAb for BMB6 → TFPI and BMTFPI → B6; gray shaded profiles, isotype-matched control mAb.

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