Effect of in vivo IFN-γ treatment on WBC count and BM cellularity. (A) Complete blood counts were obtained from experimental mice following completion of IFN-γ treatment. Data points represent the WBC count of individual mice. Bars represent the mean WBC count. ^*P < .01; ^**P < .001 comparing IFN-γ-treated versus vehicle-treated genotypic controls. (B) After 7 days of IFN-γ treatment, BM cellularity was counted. Data points represent BM cellularity of individual mice. Bars represent the mean BM cellularity. ^**P < .001 comparing IFN-γ-treated versus vehicle-treated genotypic controls. (C) TUNEL assays were conducted on BM sections from IFN-γ- or vehicle-treated Fancc^-/- and WT mice (original magnification × 400). Arrows indicate the apoptotic cells. Data are representative of 5 experimental mice in each group.