Competitive inhibition of FGF-2 binding by IL-1β ¹²⁵I-FGF-2 was incubated with the fibrinogen immobilized on Sepharose beads. Increasing concentrations of unlabeled IL-1β were used to competitively inhibit the binding of ¹²⁵I-FGF-2 to fibrinogen. Each point represents mean ± SD of 3 separate experiments.