GO-Scan classifications of 385 significantly differentially expressed genes. The x axis reflects the number of genes in a particular category of annotations from our list of 385 genes (generated using a less stringent multiple comparisons correction: false discovery rate ≤ 10%). Blue: observed number; yellow: expected number, based on the total number of genes on the chip given each annotation term multiplied by the average differential expression rate (number of differentially expressed, annotated genes/number of annotated genes). Annotation terms were selected from GO-Scan when they were significantly overrepresented in the list of differentially expressed genes. Significance was determined with a Fisher exact test and P less than or equal to .01. Individual genes from selected categories are listed in Table 3.