TRAIL expression on T cells from SLE patients with neutropenia. (A) Cell surface expression of TRAIL on T cells from SLE patients and healthy volunteers. TRAIL-positive cell percentage was significantly higher in SLE patients with neutropenia than in SLE patients without neutropenia and healthy volunteers. TRAIL-positive cell percentage was significantly higher in SLE patients without neutropenia than in healthy volunteers (*P < .01, **P < .05, Bonferroni/Dunn with one-way factorial ANOVA). (A) Representative data from 8 individual experiments. Dotted line indicates IgG control intensity; solid line indicates TRAIL expression intensity. (B) Data are shown with mean + standard deviation (n = 8 in each group). (C) T-cell cytotoxicity against autologous neutrophils. In SLE patients with neutropenia, T cells killed significantly more autologous neutrophils than in SLE patients without neutropenia and in healthy volunteers (*P < .01, **P < .05, Bonferroni/Dunn with one-way factorial ANOVA. Data were shown with mean + standard deviation, n = 8 in each group).