The SSAO inhibitor BTT-2027 blocks inflammation in vivo. Rats' air pouches were inflamed (carrageenan) or left untreated (saline), and the number of extravasated leukocytes was determined. The animals were treated with the indicated doses of SSAO inhibitors, vehicle (negative control), or dexamethasone (positive control). The numbers and subclasses of leukocytes lavaged from the air pouches are shown. The results are mean ± SEM (n = 8 in each group). The inhibitory effects of BTT-2027 on total leukocyte (P < .05) and on neutrophil (P < .05) extravasation were significant.