Cumulative incidence plots. (A) Cumulative incidence plot showing associations between transplant-related mortality (TRM) and presence or absence of the TNFd4+, 1031(C+) haplotype in donors and recipients of unrelated donor stem cell transplants. The cumulative incidence of TRM at one year after transplantation when the donor or recipient were TNFd4+, 1031(C+) haplotype-positive was 55% (43%-67%) compared with 21% (12%-30%) when both were negative (P < .01). (B) Cumulative incidence plot showing associations between transplant-related mortality and donor R2-G-C-C haplotype. The cumulative incidence of TRM at one year was significantly higher when the R2-G-C-C haplotype was present in the donor (61% [43%-79%]) compared with when it was absent from the donor (34% [25%-43%]), P = .01. (C) Cumulative incidence plot showing associations between transplant-related mortality and donor R3-G-C-C haplotype. The cumulative incidence of TRM at one year after transplantation was significantly lower when the R3-G-C-C haplotype was present in the donor (30% [19%-41%]) compared with when the haplotype was absent from the donor (53% [40%-66%]), P = .01.