Inhibition of Lewis lung carcinoma metastatic tumor growth by TFPIc23. C57/BL6J mice injected with 5 × 10⁴ tumor cells through the tail vein were treated with increasing doses of TFPIc23 intraperitoneally daily. After 11 days of treatment, tumor-bearing lungs were removed and weighed. Data are presented as the ratio of lung weight gain in animals treated with TFPIc23 (T) to the lung weight gain in control animals treated with PBS (C), ± standard error.