Average levels with standard error of iron status parameters as a function ofHFEgenotype. Twenty-three C282Y homozygotes were each matched for sex, age, and alcohol consumption with 2 persons each of the 5 other genotypes. Due to technical error, the sample from one of the 23 C282Y homozygotes was not measured, and consequently the 2 matched persons in each of the other genotypes were also excluded. Dashed lines are upper borders of reference intervals; for ferritin these borders differ between women and men. Levels in mutation carriers were tested against wild type/wild type (WT/WT) levels using Mann-Whitney U tests: ^*P = .05, ^**P = .01, ^***P = .001. Error bars indicate the standard error of the mean.