Osteoblast depletion alters the hematopoietic compartments. Two-color flow cytometric analysis of leukocyte suspensions from bone marrow, spleen, and liver isolated from Col2.3ΔTK mice injected for 25 days with PBS (control group) or with GCV. Cell suspensions were stained with antibodies against B cells (CD45R/B220 and CD19), T cells (CD3), myeloid cells (CD11b/Mac1), and erythroid progenitors (Ter119). Numbers in each region represent the proportion of cells in the total population.