The effect of IC87114 on rolling velocities of neutrophils and wall shear rate in vivo. (A) The impact of IC87114 on blood flow as a function of vessel diameter. (B) Mean rolling velocities for consecutive interacting cells (n = 20 per venule, 3 venules per animal for each experimental condition tested) in the absence or presence of inhibitor, or in p110δ^-/- mice. ^*P < .01 versus control. Data represent the mean ± SD for 200 or more cells per experimental condition.