Overall survival of patients treated with hyper-CVAD and imatinib mesylate compared with those treated with non-imatinib mesylate-containing hyper-CVAD and VAD regimens. Curves represent intention to treat, without censoring for allogeneic SCT. Differences remain significant with exclusion of the 5 patients in CR at start of hyper-CVAD and imatinib mesylate (not shown). Note: a long-term survivor at 15 years in the VAD group is not shown.