5′ Flanking genomic DNA sequence. Nucleotide sequence of the 5′ flanking genomic DNA of the human KCC1 gene is shown. Consensus sequences for potential GATA and AP-2 DNA-protein binding sites are underlined; potential Sp1-binding sites are also underlined. A indicates the transcription initiation site +1 contained within the InR. The initiator methionine is marked by a dotted line. The 5′ ends of the published cDNA (Pub) and of the 5′-most EST (EST) are shown. Sequences beginning intron 1 are in lowercase. The arrowhead indicates the end of exon 1.