Figure 1.
Figure 1. The 5′ end of the human KCC1 gene. (A) Genomic organization of the 5′ end of the human KCC1 gene. One clone containing the KCC1 gene was isolated from a human genomic DNA library. This clone spanned a distance of approximately 90 kb and contained exons 1 to 3 of the KCC1 cDNA in an approximately 13.5-kb XbaI fragment. A partial restriction map of this 13.5-kb fragment with BamHI (b) and XbaI (X) is shown. (B) Structure of the 5′ end of the human KCC1 cDNA. A diagram of the 5′ end of the human KCC1 cDNA is shown. The location of the initiation codon is shown, as is the location of intron/exon boundaries. Box denotes sequences obtained by 5′ RACE. Arrows denote oligonucleotide primers used in 5′ RACE. 5′ ends of the published cDNA and the 5′-most EST (IMAGE 5174748) are shown.

The 5end of the humanKCC1gene. (A) Genomic organization of the 5′ end of the human KCC1 gene. One clone containing the KCC1 gene was isolated from a human genomic DNA library. This clone spanned a distance of approximately 90 kb and contained exons 1 to 3 of the KCC1 cDNA in an approximately 13.5-kb XbaI fragment. A partial restriction map of this 13.5-kb fragment with BamHI (b) and XbaI (X) is shown. (B) Structure of the 5′ end of the human KCC1 cDNA. A diagram of the 5′ end of the human KCC1 cDNA is shown. The location of the initiation codon is shown, as is the location of intron/exon boundaries. Box denotes sequences obtained by 5′ RACE. Arrows denote oligonucleotide primers used in 5′ RACE. 5′ ends of the published cDNA and the 5′-most EST (IMAGE 5174748) are shown.

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