Expression of VWF, E-selectin, and VEGFR-3 in HEV in vivo. Double immunofluorescence staining of human tonsil sections with MECA-79 (red) and anti-VWF (A), anti–E-selectin (B), or anti–VEGFR-3 (C) antibodies (green) reveals expression of these markers in MECA-79–positive HEV in situ (original magnification, × 100).