Characterization of recombinant fibrinogens. Coomassie-stained 10% SDS-PAGE run under reducing conditions; normal recombinant fibrinogen (lane 1), γN308K fibrinogen (lane 2), γN308I fibrinogen (lane 3), γN308A fibrinogen (lane 4), plasma fibrinogen from Matsumoto II patient (lane 5), and plasma fibrinogen from normal individual (lane 6). Positions of the molecular markers are indicated on the left (M).