Figure 1.
Figure 1. Hepc1 quantification and nonheme iron concentration in livers of 4-week-old mice. Hepc1 amount was quantified by real-time PCR and normalized to the amount of gapdh as described in “Study design.” Results are expressed as mean ± SD for n animals. *P < .01; **P < .001; ***P < .0001. The Kruskal-Wallis test was P < .0001 (mean rank: Hfe-/-Usf2+/-, 10.75; Hfe-/-Usf2+/+, 21.35; Hfe+/-Usf2+/-, 30.50; Hfe+/-Usf2+/+, 34.25). (B) Nonheme iron concentrations in liver samples from 4-week old mice with different Hfe and Usf2 genotypes. Iron content was measured in 2 pieces of liver for each mouse. Results are expressed as mean ± SD for n animals. The Kruskal-Wallis test was P < .0001 (mean rank: Hfe-/-Usf2+/-, 30.29; Hfe-/-Usf2+/+, 29.70; Hfe+/-Usf2+/-, 11.50; Hfe+/-Usf2+/+, 5.50).

Hepc1 quantification and nonheme iron concentration in livers of 4-week-old mice.Hepc1 amount was quantified by real-time PCR and normalized to the amount of gapdh as described in “Study design.” Results are expressed as mean ± SD for n animals. *P < .01; **P < .001; ***P < .0001. The Kruskal-Wallis test was P < .0001 (mean rank: Hfe-/-Usf2+/-, 10.75; Hfe-/-Usf2+/+, 21.35; Hfe+/-Usf2+/-, 30.50; Hfe+/-Usf2+/+, 34.25). (B) Nonheme iron concentrations in liver samples from 4-week old mice with different Hfe and Usf2 genotypes. Iron content was measured in 2 pieces of liver for each mouse. Results are expressed as mean ± SD for n animals. The Kruskal-Wallis test was P < .0001 (mean rank: Hfe-/-Usf2+/-, 30.29; Hfe-/-Usf2+/+, 29.70; Hfe+/-Usf2+/-, 11.50; Hfe+/-Usf2+/+, 5.50).

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