Figure 1.
![Figure 1. Cytokine gene expression profiles in adult chronic ITP patients. Expression (mean ± SEM) of the cytokines studied at the mRNA level in control subjects, patients in active disease phase (PLT count < 100 × 109/L [< 100 000/mm3]), and patients in hematologic remission by peripheral blood mononuclear cells ex vivo and after in vitro stimulation with PMA and ionomycin (P/I). Asterisks denote significance using unpaired 2-tail t test (*P < .05; **P < .01). Comparisons among subject groups (controls, patients with active disease, and patients in remission) were made under the same experimental conditions (ex vivo PBMCs or stimulated PBMCs) for each cytokine separately.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/103/7/10.1182_blood-2003-07-2268/6/zh80070459070001.jpeg?Expires=1724999184&Signature=Ksxy1mCD3DOtRzfKzjojfa--8eJULvaeOq6xACC60SnyMkJUklnsCBEXGOSQnI1PAen9AVU7ew8FptBNbPEY2ZYyeVHNHnvqtVsSxQjhF-hKp-XESFJN~fLYiXw6KE0tCe-0rQKIaGKQHUFHKzVhF0T1UV3eYcIwc8dkOVSQ5goAo5ey8eR5Jas44mhbLUGLVGL7H2HYRIgYLlOrH0wlIvh90FfPTCmryiFjmTRmdsJsawebQ4racnFwNVoQVbNf8eTl9eeV5z0Jq~i1bORx7NP1jQ-3MyD3uvtAV8XAsblHTOwGQbSkkbme20-xV5-VqdclK91keM6xbZV1kq5HIA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Cytokine gene expression profiles in adult chronic ITP patients. Expression (mean ± SEM) of the cytokines studied at the mRNA level in control subjects, patients in active disease phase (PLT count < 100 × 109/L [< 100 000/mm3]), and patients in hematologic remission by peripheral blood mononuclear cells ex vivo and after in vitro stimulation with PMA and ionomycin (P/I). Asterisks denote significance using unpaired 2-tail t test (*P < .05; **P < .01). Comparisons among subject groups (controls, patients with active disease, and patients in remission) were made under the same experimental conditions (ex vivo PBMCs or stimulated PBMCs) for each cytokine separately.
