Figure 3.
Partition for SLL, MZL, MCL, and borderline samples using the 44-genes predictor. (A) Preliminary group samples were correlated to SLL, MZL, and MCL mean profiles. The horizontal axis represents correlations with the MCL mean profile (RMCL) and the vertical axis represents correlations with the SLL mean profile (RSLL). The SLL samples are represented in orange, the splenic MZL samples in blue, and the MCL samples in pink. Cases reclassified as borderline cases are represented in brown. Three of the 6 cases were hybridized twice. Each axis represents the positive value of one subtype. (B) Gene-expression data of the 44 selected genes used for the diagnostic predictor. All samples, the preliminary group, and the validation group samples were clustered according to the expression data of the 44 genes of the diagnostic predictor. Validation group samples were blind analyzed and are marked with a black dot. Note the small branch on the left side of the dendogram containing 4 unpredictable samples. See Table S2 for gene names.

Partition for SLL, MZL, MCL, and borderline samples using the 44-genes predictor. (A) Preliminary group samples were correlated to SLL, MZL, and MCL mean profiles. The horizontal axis represents correlations with the MCL mean profile (RMCL) and the vertical axis represents correlations with the SLL mean profile (RSLL). The SLL samples are represented in orange, the splenic MZL samples in blue, and the MCL samples in pink. Cases reclassified as borderline cases are represented in brown. Three of the 6 cases were hybridized twice. Each axis represents the positive value of one subtype. (B) Gene-expression data of the 44 selected genes used for the diagnostic predictor. All samples, the preliminary group, and the validation group samples were clustered according to the expression data of the 44 genes of the diagnostic predictor. Validation group samples were blind analyzed and are marked with a black dot. Note the small branch on the left side of the dendogram containing 4 unpredictable samples. See Table S2 for gene names.

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