Figure 4.
Figure 4. Bcl-XL mice develop plasma cell pathology. (A) H&E-stained section of a kidney from a Bcl-XL mouse with a hyaline tubular cast (asterisk) and a perivascular focus of plasma cells (arrow). (B) CD138-immunostained (red reaction product) kidney section from a 3′KE/Bcl-XL mouse, counterstained with hematoxylin. (C) H&E-stained section of a femur of a 3′KE/Bcl-XL mouse demonstrating a bone marrow plasma cell focus (arrow). (D) H&E-stained section of a lymph node of a 3′KE/Bcl-XL mouse with plasma cell aggregates. Original magnifications: × 40 (A,D) and × 100 (B-C).

Bcl-XL mice develop plasma cell pathology. (A) H&E-stained section of a kidney from a Bcl-XL mouse with a hyaline tubular cast (asterisk) and a perivascular focus of plasma cells (arrow). (B) CD138-immunostained (red reaction product) kidney section from a 3′KE/Bcl-XL mouse, counterstained with hematoxylin. (C) H&E-stained section of a femur of a 3′KE/Bcl-XL mouse demonstrating a bone marrow plasma cell focus (arrow). (D) H&E-stained section of a lymph node of a 3′KE/Bcl-XL mouse with plasma cell aggregates. Original magnifications: × 40 (A,D) and × 100 (B-C).

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