Figure 5.
Figure 5. Vδ1 and Vδ2 T-cell migration in response to homeostatic (SDF-1/CXCL12 and 6CK/SLC/CCL21) or inflammatory (IP-10/CXCL10) chemokines. Vδ2 (A-C) and Vδ1 (D-F) γδ T-cell clones, with distinct expression of CXCR3 and CXCR4, as indicated, were assayed for transmigration across HUVEC monolayers at different time points in the absence (Nil, ▵) or presence of the chemokines SDF-1/CXCL12 (), IP-10/CXCL10 (▴), or 6CK/SLC/CCL21 (•), all at 50 ng/mL. Results are expressed as percentage of transendothelial migration, calculated as described in “Patients, materials, and methods” and are the mean ± SD from 3 independent experiments. *Student t test; P < .05.

Vδ1 and Vδ2 T-cell migration in response to homeostatic (SDF-1/CXCL12 and 6CK/SLC/CCL21) or inflammatory (IP-10/CXCL10) chemokines. Vδ2 (A-C) and Vδ1 (D-F) γδ T-cell clones, with distinct expression of CXCR3 and CXCR4, as indicated, were assayed for transmigration across HUVEC monolayers at different time points in the absence (Nil, ▵) or presence of the chemokines SDF-1/CXCL12 (), IP-10/CXCL10 (▴), or 6CK/SLC/CCL21 (•), all at 50 ng/mL. Results are expressed as percentage of transendothelial migration, calculated as described in “Patients, materials, and methods” and are the mean ± SD from 3 independent experiments. *Student t test; P < .05.

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