Proliferative and cytokine responses to mitogen and antigens by lymphocytes from HL patients and controls. The y-axis shows cytokine (IL-10, IL-4, and IFN-γ) and proliferative responses measured after 5 days' culture. Cells from healthy volunteer PBMCs (n = 20), HL patient PBMCs (n = 24), HLILs (n = 24), or control nodes (n = 45) were either left unstimuated or stimulated with mitogen (ConA), recall antigen (PPD), or primary antigen (KLH). The mean of the replicates for each patient is shown: the solid line on each plot shows the median responses obtained for each patient group.