Figure 5.
Figure 5. RIT of BCL1 lymphoma using a panel of anti–B-cell mAbs. BCL1 cells (105 intravenously) were given on day 0, and RIT treatments were administered by intravenous injection 10 days later (500 μg mAbs with or without 9.25 MBq conjugated 131I). Unlabeled anti-MHCII had no discernible therapeutic effect and anti-Id and anti-CD19 had very modest improvements in survival of just a few days. A similar therapeutic effect was seen for all 3 radioimmunconjugates (9.25MBq 131I-labeled anti-MHCII, anti-CD19, and anti-Id).

RIT of BCL1 lymphoma using a panel of anti–B-cell mAbs. BCL1 cells (105 intravenously) were given on day 0, and RIT treatments were administered by intravenous injection 10 days later (500 μg mAbs with or without 9.25 MBq conjugated 131I). Unlabeled anti-MHCII had no discernible therapeutic effect and anti-Id and anti-CD19 had very modest improvements in survival of just a few days. A similar therapeutic effect was seen for all 3 radioimmunconjugates (9.25MBq 131I-labeled anti-MHCII, anti-CD19, and anti-Id).

Close Modal

or Create an Account

Close Modal
Close Modal