Inhibition of Vegfr2-luc expression and wound healing by DEX. (A) Punch wounds 8 mm in diameter were generated on the backs of female Vegfr2-luc mice (n = 8). The mice were intraperitoneally injected with luciferin and imaged for 5 minutes at various time points after wounding. The day 0 image was taken immediately after wounding. Mice were intraperitoneally injected with DEX (10 mg/kg) or saline daily beginning 1 day before the wounding. (B) Quantification of luciferase expression (photons/sec) from the wound area with LivingImage software (Xenogen). Data are shown as mean ± SE. (C) Wound area was measured and shown as a percentage of the initial wound area on day 0. Data presented are mean ± SE.