Figure 4.
![Figure 4. Acute GVHD incidence is significantly reduced in SCT recipients who received donor PBSC grafts, with the lowest fractions of CD4+ and CD8+ T cells expressing CD25. (A) Actuarial incidence of acute GVHD was significantly lower in SCT patients receiving a lower fraction of CD4+CD25+ T cells than others (7% for recipients with donors in the lowest quartile of CD25 expression [solid line] vs 47% for others [dashed line]; P = .01). (B) Actuarial incidence of acute GVHD was also lower in SCT patients receiving a lower fraction of CD8+CD25+ T cells than others (13% for recipients with donors in the lowest quartile of CD25 expression [solid line] vs 44% for others [dashed line]; P = .05).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/103/3/10.1182_blood-2003-06-2085/6/zh80030455890004.jpeg?Expires=1723256395&Signature=PNa3vbIC4rqTtxslmxZ1Gfb1c-B4kI5g-KvXdAh2skrYMgDKFfH70ESL3YjuelIUdG64oizcxrhNGQ1FAu~rPTl8bw9xklVHT2i1q7xB6DhIXueVC91thZKopz8JCTOtAEaE4~EL4~bwIqzwWLft5lQORIDcQ5ANuB2r3rNj5U3ohXwoUqbomdnPYa6fnvfwW8eSrcNn9ZkzPtBmAw3V~E5YD7mPJGuWvasRXHiB-~82jIFR3eZHDIvvMmXO0N5fJYz03OHAqWFapoQKRiiLEEAH-64vrjHDrAY~pXaVgXjk8Zj0wQItnbf02g8x0WoZlknmRFt1Bw~fQmwxrS9MGg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Acute GVHD incidence is significantly reduced in SCT recipients who received donor PBSC grafts, with the lowest fractions of CD4+ and CD8+ T cells expressing CD25. (A) Actuarial incidence of acute GVHD was significantly lower in SCT patients receiving a lower fraction of CD4+CD25+ T cells than others (7% for recipients with donors in the lowest quartile of CD25 expression [solid line] vs 47% for others [dashed line]; P = .01). (B) Actuarial incidence of acute GVHD was also lower in SCT patients receiving a lower fraction of CD8+CD25+ T cells than others (13% for recipients with donors in the lowest quartile of CD25 expression [solid line] vs 44% for others [dashed line]; P = .05).
