Comparison of the in vitro effects of alphastatin and FgnE. (A) HuDMEC migration across a collagen-coated filter in response to medium alone or medium containing 10 ng/mL VEGF. (B) Tubule formation by HuDMECs on GF-reduced Matrigel in response to medium alone (control) or medium containing 10 ng/mL VEGF. All data shown are means ± SEM. *P < .02 compared with respective “no protein” groups. ^P < .05 compared with respective alphastatin groups.