Figure 5.
Figure 5. Phenotype of lentivirus- and oncoretrovirus-transduced baboon CD34-enriched cells. (A) Percent of cells positive for the indicated CD markers in the mock (□), oncoretrovirus (▪), and lentivirus (▤) transduction cultures. (B) Percent of oncoretrovirally transduced (▪) and lentivirally transduced (▤) cells in the total leukocyte (PBL), granulocyte/monocyte (CD13 and CD14), progenitor (CD34), and dendritic (CD83) subsets. Asterisks denote a significant difference (P < .05) in transduction efficiency between oncoretrovirus and lentivirus vectors. For both analyses, over 50 000 FSC/SSC gated, PI-negative events were analyzed for each sample.

Phenotype of lentivirus- and oncoretrovirus-transduced baboon CD34-enriched cells. (A) Percent of cells positive for the indicated CD markers in the mock (□), oncoretrovirus (▪), and lentivirus (▤) transduction cultures. (B) Percent of oncoretrovirally transduced (▪) and lentivirally transduced (▤) cells in the total leukocyte (PBL), granulocyte/monocyte (CD13 and CD14), progenitor (CD34), and dendritic (CD83) subsets. Asterisks denote a significant difference (P < .05) in transduction efficiency between oncoretrovirus and lentivirus vectors. For both analyses, over 50 000 FSC/SSC gated, PI-negative events were analyzed for each sample.

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