The numbers of CAFCs in peripheral blood are decreased after pretreatment with ciprofloxacin and polymyxin B. Balb/c mice were treated with 100 mg/L ciprofloxacin, 70 mg/L polymyxin B, and 20 mg/L saccharose added to their drinking water. The antibiotic treatment was continued and mice were mobilized with a single intraperitoneal injection of 30 μg IL-8. At 20 minutes after the IL-8 injection, mice were killed and blood was harvested. Results are expressed as means ± SD. *P < .05 compared with the controls.