IL-8–induced mobilization is significantly reduced after treatment with metronidazol. Mice were receiving either normal drinking water (n = 5), water treated with 500 mg/L metronidazol and 20 g/L saccharose (n = 5), or water treated with 500 mg/L metronidazol, 100 mg/L ciprofloxacin, and 20 g/L saccharose (n = 5) for 1 week. Mice were mobilized with a single intraperitoneal injection of 30 μg IL-8. At 20 minutes after the IL-8 injection, the mice were killed and blood was harvested. Results are expressed as means ± SD. *P < .05 compared with the controls (n = 2).