Figure 4.
Prothrombin haplotypes differentially influence reporter gene activity and mRNA expression in stably transfected cells. Comparison of normalized corrected luciferase reporter gene activity (NPT corrected, □) and luciferase mRNA expression (neo-R expression corrected, ▤) relative output for plasmids representing different prothrombin haplotypes. Cells are stably transfected and polyclonal; 6 experiments were performed in duplicate. Error bars represent the standard error of mean. Results for the pF2-wt-neo-AG plasmid are used for normalization and have no error bars.