Figure 4.
Figure 4. Prothrombin haplotypes differentially influence reporter gene activity and mRNA expression in stably transfected cells. Comparison of normalized corrected luciferase reporter gene activity (NPT corrected, □) and luciferase mRNA expression (neo-R expression corrected, ▤) relative output for plasmids representing different prothrombin haplotypes. Cells are stably transfected and polyclonal; 6 experiments were performed in duplicate. Error bars represent the standard error of mean. Results for the pF2-wt-neo-AG plasmid are used for normalization and have no error bars.

Prothrombin haplotypes differentially influence reporter gene activity and mRNA expression in stably transfected cells. Comparison of normalized corrected luciferase reporter gene activity (NPT corrected, □) and luciferase mRNA expression (neo-R expression corrected, ▤) relative output for plasmids representing different prothrombin haplotypes. Cells are stably transfected and polyclonal; 6 experiments were performed in duplicate. Error bars represent the standard error of mean. Results for the pF2-wt-neo-AG plasmid are used for normalization and have no error bars.

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