Correction of abnormal RBC morphology in lenti/β^AS3rescued transplants. (A) Blood smear from a mock-transplanted animal with characteristic sickled erythrocytes and a pronounced reticulocytosis. (B-C) Two representative primary transplant recipients of β^AS3-transduced stem cells. No sickled cells were observed in any fields examined. (D) Wild-type C57Bl6 control. Original magnification × 120. Blood smears were stained with Wright-Giemsa.