American Society of Hematology

Figure 5.

$Figure 5. Inhibition of Hsp27 sensitizes Dex-refractory patient MM cells to Dex. Purified MM cells (CD138+) from Dex-refractory patients (patients A-C) were treated with Dex, eucalyptus bioflavonoids, or Dex plus eucalyptus bioflavonoids for 48 hours, and analyzed for apoptosis by flow cytometric analysis using dualfluorescence staining with DNA-binding fluorochrome Hoechst 33342 (HO) and propidium iodide (PI). PI-- and HO+ stained cells represent apoptotic cells. Error bars represent standard deviation.$

Inhibition of Hsp27 sensitizes Dex-refractory patient MM cells to Dex. Purified MM cells (CD138⁺) from Dex-refractory patients (patients A-C) were treated with Dex, eucalyptus bioflavonoids, or Dex plus eucalyptus bioflavonoids for 48 hours, and analyzed for apoptosis by flow cytometric analysis using dualfluorescence staining with DNA-binding fluorochrome Hoechst 33342 (HO) and propidium iodide (PI). PI^-- and HO+ stained cells represent apoptotic cells. Error bars represent standard deviation.

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