cDNA macroarray. (A) Growth factors and receptors. (B) Cytokines, chemokines, and adhesion molecules. (C) Matrix, proteases, and inhibitors. (D) Other angiogenesis-related genes. The figure summarizes the expression profile of 96 angiogenesis-related genes of 10 MMEC and 3 HUVEC samples. Genes were clustered in 4 functional groups. Only results for genes whose expression in MMECs and/or HUVECs was detectable are shown; no bar is shown for instances when gene expression was undetectable. The gene symbol is reported on the x-axis, and its expression is shown as a percentage of GAPDH housekeeping gene. Data shown are mean ± 1 SD for both MMECs (▪) and HUVECs (□). ^* Indicates the difference of gene expression between the MMEC and HUVEC is statistically significant (P < .05 or better by Mann-Whitney nonparametric test).