Figure 3.
Colony-forming activity of hematopoietic progenitor cells from OSMR+/+ and OSMR–/– mice. CFU-Es (A,D), CFU-GEMMs/CFU-MEs/BFU-Es (B,E), and GM-CFCs (C,F) from hematopoietic cells of OSMR+/+ and OSMR–/– mice are shown. The figure shows mean total colony number ± SD (n = 5 to 7) in triplicate cultures containing 25 000 BM cells (A-C) or 100 000 spleen cells (D-F) stimulated with final concentrations of IL-3 at 10 ng/mL, SCF at 80 ng/mL, and EPO at 4 U/mL. *P < .05 between wild-type and mutant mice. †P < .01 between wild-type and mutant mice.

Colony-forming activity of hematopoietic progenitor cells from OSMR+/+ and OSMR–/– mice. CFU-Es (A,D), CFU-GEMMs/CFU-MEs/BFU-Es (B,E), and GM-CFCs (C,F) from hematopoietic cells of OSMR+/+ and OSMR–/– mice are shown. The figure shows mean total colony number ± SD (n = 5 to 7) in triplicate cultures containing 25 000 BM cells (A-C) or 100 000 spleen cells (D-F) stimulated with final concentrations of IL-3 at 10 ng/mL, SCF at 80 ng/mL, and EPO at 4 U/mL. *P < .05 between wild-type and mutant mice. †P < .01 between wild-type and mutant mice.

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