Splenomegaly temporally correlates with thrombocytopenia during B hermsii infection. (A) 129Sv/C57BL6 mice were inoculated intraperitoneally with 10⁶B hermsii DAH. On each of the indicated days after infection, 2 mice were killed, and spirochete counts (i), platelet counts (ii), and spleen (iii) and liver (iv) weights were determined. (B) Spirochetemia (i) and thrombocytopenia (ii) in C57BL6 mice after splenectomy.