OS after IPS. Overall survival after diagnosis of IPS stratified by maximum serum creatinine concentration (A) or vasopressor use (B) among 81 patients who acquired IPS after allogeneic HSCT. (A) Overall survival of the patients who had renal insufficiency, defined as maximum serum creatinine concentration of 2 mg/dL or more, within 3 days of IPS onset (broken line; n = 23) was lower than that of patients without renal insufficiency (solid line; n = 49) (P = .001). (B) Overall survival of patients who required vasopressor within 3 days of IPS onset (broken line; n = 10) was lower than that of patients who did not (solid line; n = 62) (P = .001). Nine patients who died within 3 days of IPS onset were excluded.